NCT02509949

Effects of Dexmedetomidine on Delirium After Living Donor Renal Transplantation in Adult Patients

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Tao Zhang · Academic / Other
• Sex: All
• Age: 18 Years – 59 Years
• Healthy volunteers: Not accepted

Summary

Delirium, an acute change in mental status, is a serious medical complication among hospitalized patients. Syndrome of delirium involves agitation, sleep disturbance, affective disorders and cognitive disruptions. One vulnerable period for developing delirium is in the postoperative days. Postoperative delirium often initiates a cascade of adverse consequences including an increase in length of stay and hospital costs, and greater mortality. The investigators have observed that the incidence of postoperative delirium in patients after renal transplantation is about 20-30% in our hospital. Several studies have revealed that dexmedetomidine, as a widely used sedative during anesthesia, can decrease the incidence of postoperative delirium after cardiac surgery. The investigators aim to examine whether administration of dexmedetomidine can reduce postoperative delirium after living donor renal transplantation in adult patients.

Conditions

• Postoperative Delirium After Living Donor Renal Transplantation

Interventions

Type	Name	Description
DRUG	Dexmedetomidine
DRUG	Saline

Timeline

• Start date: 2015-05-01
• Primary completion: 2019-09-01
• First posted: 2015-07-28
• Last updated: 2018-06-12

Locations

1 site across 1 country: China