NCT02509351

Could Pre-operative Rectal Misoprostol Reduce Intra-operative Blood Loss During Ceserean Section?

Randomized, Placebo-controlled Double Blind Study of Preoperative Misorostol for Reduction of Intraoperative Bleeding in Women Delivered by Ceserean Section

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 280 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

* Misoprostol reduces the uterine bleeding after cesarean delivery without harmful effects on either mother or baby. * The aim of the this study is to address if there is any benefits 'regarding the intra-operative blood loss' from preoperative rectal administration of 400 mic of Misoprostol in addition to the routinely administrated 10 units of oxytocin

Detailed description

Research question: In women undergoing elective ceserean section, is preoperative 400 mic Misoprostol reduce intra-operative blood loss? Research hypothesis: pre-operative Misoprostol doesn't reduce intraoperative blood loss in women undergoing ceserean section

Conditions

• Postpartum Haemorrhage

Interventions

Type	Name	Description
DRUG	misoprostol	400 microgram of misoprostol is given preoperatively in patients undergoing elective cesarean section
DRUG	placeboo	women will recive 2 identical tablets as placeboo

Timeline

• Start date: 2015-10-01
• Primary completion: 2016-11-01
• Completion: 2016-11-01
• First posted: 2015-07-28
• Last updated: 2016-11-10

Locations

1 site across 1 country: Egypt