NCT02504164

Effect of Midazolam Premedication on the Satisfaction Levels of Patients After Endoscopic Submucosal Dissection

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: Yonsei University · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

Endoscopic submucosal dissection is commonly performed under light to moderate sedation, and minimizing patient movement is of key importance for successful outcome. Propofol has widely replaced benzodiazepines as sedative drug of choice, and has been reported to enhance the quality of procedure in our past study. However, despite higher satisfaction scores of the endoscopists and faster post-procedural recovery, patient satisfaction scores were found to be higher in patients that received midazolam and meperidine instead of propofol and remifentanil. This seems to be due to the anterograde amnestic effects of midazolam rather than the quality of sedation itself. Investigator hypothesized that by premedicating the patient with low lose midazolam before receiving sedation for ESD with propofol and fentanyl, patient satisfaction would be enhanced without affecting endoscopic performance.

Conditions

• Early Gastric Cancer
• Gastric Adenoma

Interventions

Type	Name	Description
DRUG	midazolam 0.02mg/kg
DRUG	No premedication	No premedication before sedation for endoscopic submucosal dissection

Timeline

• Start date: 2014-09-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2015-07-21
• Last updated: 2016-03-07

Locations

1 site across 1 country: South Korea