NCT02504034

Interventional Radiology for the Treatment of Symptomatic Portal Hypertension in Patients With Cavernous Transformation of Portal Vein

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 1 Year – 80 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the values of portosystemic shunt and other interventional radiology approaches for treatment of symptomatic portal hypertension in patients with cavernous transformation of portal vein.

Conditions

• Portal Vein, Cavernous Transformation Of
• Hypertension, Portal

Interventions

Type	Name	Description
PROCEDURE	Transhepatic portosystemic shunt	Portal vein (PV) was punctured with a 22-gauge chiba needle. A 0.018-inch guidewire was advanced through the needle into PV lumen. The needle was exchanged and a 6-French sheath inserted over the wire. Then middle hepatic vein (MHV) was punctured with a 20-gauge reformed needle through the transhepatic sheath. Another 0.018-inch guidewire was advanced through the needle into right internal jugular vein and then snared out of body. A 0.035-inch, 260-cm-long stiff shaft wire was introduced through the transjugular sheath and manipulated into main portal vein (MPV) and then into SMV. The parenchymal tract was dilated with balloon catheter, then one or more bare metal stents and one or more covered stents were inserted to line the parenchymal tract.
DEVICE	6-French sheath
DEVICE	22-gauge chiba needle
DEVICE	260-cm-long stiff shaft wire
DEVICE	Balloon catheter
DEVICE	Bare metal stent
DEVICE	Covered stent

Timeline

• Start date: 2010-10-01
• Primary completion: 2020-12-01
• First posted: 2015-07-21
• Last updated: 2015-07-21

Locations

1 site across 1 country: China