Trials / Completed
CompletedNCT02496585
Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis
Phase II Double-Blind, Randomized, Placebo Controlled Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 34 (actual)
- Sponsor
- Memorial Sloan Kettering Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to find out what effects, good and/or bad, the drug nintedanib in combination with steroids, has on the lungs. Furthermore, such treatments' side effects will be studied together with quality of life. In addition, the investigators would like to determine whether they can find markers in the blood which predict worsening lung injury.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Nintedanib | |
| DRUG | Prednisone | |
| OTHER | Placebo |
Timeline
- Start date
- 2015-07-08
- Primary completion
- 2024-04-12
- Completion
- 2024-04-12
- First posted
- 2015-07-14
- Last updated
- 2025-04-16
- Results posted
- 2025-04-16
Locations
12 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT02496585. Inclusion in this directory is not an endorsement.