Trials / Completed
CompletedNCT02496455
The Impact of the SCN9A Gene Polymorphism on Postoperative Pain
The Impact of the Single Nucleotide Polymorphisms rs6746030,rs7604448, rs10930214, s7595255 in SCN9A Gene on Postoperative Pain and Analgesic Consumption After Cesarean Section
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 200 (actual)
- Sponsor
- Tokat Gaziosmanpasa University · Academic / Other
- Sex
- Female
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study to determine the association between postoperative pain after cesarean section and several single nucleotide polymorphisms in SCN9A sodium channels gene.
Detailed description
SCN9A gene encodes an alpha subunit of the voltage-gated sodium channel (Nav1.7) and polymorphisms of this gene are associated with severe pain disorders. The impact of the polymorphisms in SCN9A on postoperative pain and opioid consumption after cesarean section is unclear.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | cesarean section | Women in 36 to 40 weeks of pregnancy undergoing cesarean section by Pfannenstiel technique |
| DRUG | Opioid Tramadol | Tramadol will be administered via patient controlled analgesia (PCA) pump in the postoperative period |
Timeline
- Start date
- 2015-08-01
- Primary completion
- 2017-05-01
- Completion
- 2017-11-01
- First posted
- 2015-07-14
- Last updated
- 2017-11-21
Locations
1 site across 1 country: Turkey (Türkiye)
Source: ClinicalTrials.gov record NCT02496455. Inclusion in this directory is not an endorsement.