Trials / Completed
CompletedNCT02496234
The Use of Aging Biomarkers to Predict Adverse Outcomes After Cardiac Surgery
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 186 (actual)
- Sponsor
- Sapere Bio · Industry
- Sex
- All
- Age
- 50 Years
- Healthy volunteers
- Not accepted
Summary
Cardiac surgery associated acute kidney injury (CSA-AKI) has been recognized as the second most common cause of hospital acquired AKI. The development of CSA-AKI is independently associated with an increased risk of in-hospital death. There are currently no biomarkers that could identify patients at higher risk for AKI and current risk predictor scores that are based on clinical and demographic information are inadequate. Therefore, a diagnostic test for predicting AKI risk in this clinical context would assist clinicians to optimize surgical strategy and postoperative care to prevent CSA-AKI occurrence and improve patient outcomes. The primary purpose of this study is to measure the association between baseline expression of senescence markers in blood using SenesceTest and the occurrence of CSA-AKI post surgery.
Conditions
Timeline
- Start date
- 2015-07-01
- Primary completion
- 2016-07-01
- Completion
- 2016-07-01
- First posted
- 2015-07-14
- Last updated
- 2016-11-23
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02496234. Inclusion in this directory is not an endorsement.