NCT02495207

A Comparison Between Conventional Surgery and Piezosurgery

A Histo-immunological Comparative Study of Bone Cutting by Conventional Surgery and Piezosurgery on the Secretion of Heat Shock Protein 70 (HSP70) and on the Bone Cells

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Damascus University · Academic / Other
• Sex: All
• Age: 16 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

Evaluation of the effect of conventional and piezo-surgery on the secretion of Heat Shock Protein (HSP70) and on the vial bone cells at the peripheral bone cut sides after the removal of impacted mandibular third molars on both sides of the jaw.

Detailed description

The study is about measuring the amount of HSP70 using Elisa kit for detecting HSP70 and mason trichrome for histological findings in which the study samples are patients who have bilateral impacted mandibular third molar to be extracted with bone removal. First we collect bone sample for mason trichrome with either method then we collect the second samples after removing most of the bones cover the impacted third molar for checking HSP70 levels. Then the bone samples are treated using a special protocol to eliminate the protein from bone samples for the Elisa analysis. The other bone samples are going to be studied under the microscope.

Conditions

• Third Molars Extraction

Interventions

Type	Name	Description
DEVICE	Piezosurgery	This intervention is dependent on use of piezosurgery to conduct the required bone cuts to remove third molars.

Timeline

• Start date: 2014-06-01
• Primary completion: 2016-03-14
• Completion: 2017-04-14
• First posted: 2015-07-13
• Last updated: 2017-07-27

Locations

1 site across 1 country: Syria