Trials / Unknown
UnknownNCT02493543
Autoantibodies on Spinal Cord Injury
Role of Autoantibodies in Spontaneous Functional Recovery After Spinal Cord Injury
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 110 (estimated)
- Sponsor
- Hospital Nacional de Parapléjicos de Toledo · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to determine the autoantibody profiles after spinal cord injury and their role in spontaneous functional recovery.
Detailed description
Most patients experience variable degrees of functional recovery after spinal cord injury (SCI), predominantly in the first months after lesion. In SCI animal models, autoantibodies are pathogenic and their titers rise up at the time when spontaneous recovery stops. The aim of this study is to determine the autoantibody profiles after SCI and to infer their relation with functional recovery. To achieve this, autoantibody profiles, biochemical, hematological and immune-related parameters (cytokines, chemokines and growth factors) will be determined from a serum blood sample and functional recovery will be evaluated accordingly to standardized scales.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Blood collection | Blood collection from the subject's arm |
Timeline
- Start date
- 2014-10-17
- Primary completion
- 2018-04-01
- Completion
- 2018-04-01
- First posted
- 2015-07-09
- Last updated
- 2018-02-23
Locations
2 sites across 2 countries: Germany, Spain
Source: ClinicalTrials.gov record NCT02493543. Inclusion in this directory is not an endorsement.