NCT02492464

Effects of 10 mg Monacolins on Vascular Health: a Clinical Trial

Double-blind, Randomized Clinical Trial on the Middle-term Effect of the Red Yeast Rice Intake on Endothelial Function and Arterial Stiffness in Subjects With Suboptimal LDL-cholesterol Level in the Context of the Mediterranean Diet

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: University of Bologna · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This will be a double-blind randomized clinical trial carried out on subjects with suboptimal control of LDL-cholesterolemia, following a Mediterranean diet, and treated with a red yeast rice extract (containing 10 mg monacolin K per daily dose) or placebo, in order to evaluate the middle-term effects on vascular health evaluated by non invasive methods (Vicorder(R) apparatus)

Conditions

• Atherosclerosis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Red yeast rice	1 capsule to be taken before to sleep, each day, for 6 months
DIETARY_SUPPLEMENT	Placebo

Timeline

• Start date: 2015-05-01
• Primary completion: 2015-06-01
• Completion: 2015-12-01
• First posted: 2015-07-08
• Last updated: 2024-02-01

Locations

1 site across 1 country: Italy