NCT02492373

Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser

Effect of Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation Following Q-switched Nd:YAG 532 nm Laser for Treatment of Facial Lentigines - A Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 21 (actual)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

To investigate the benefit of the application of topical high potency steroid on the incidence of post inflammatory hyperpigmentation after laser treatment.

Detailed description

* The incidence of post inflammatory hyperpigmentation (PIH) after treating lentigines with Q-switched Nd:YAG laser was 78.3%. * It has been found that the incidence of PIH decreased to 40% after applied topical high potency steroid 2 days after the laser treatment. * By these anti-inflammatory and anti-PIH effects of the high potency steroid, the investigators aimed that the application of steroid 2 days before and 2 days after the laser treatment would be better reduction in the incidence of PIH after Q-switched Nd:YAG laser.

Conditions

• Lentigines
• Post Inflammatory Hyperpigmentation

Interventions

Type	Name	Description
DRUG	topical 0.05% Clobetasol propionate ointment	Apply only on the treated area twice a day as mentions
DEVICE	Q switched Nd:YAG laser 532 nm	Treatment of facial lentigines. The energy using depends on the endpoint of immediate whitening of the lesions.

Timeline

• Start date: 2015-02-01
• Primary completion: 2016-05-01
• Completion: 2016-05-01
• First posted: 2015-07-08
• Last updated: 2016-06-01

Locations

1 site across 1 country: Thailand