Trials / Unknown
UnknownNCT02485184
TIPS vs Endoscopic Therapy for Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis
TIPS Versus Endoscopic Therapy for the Prevention of Variceal Rebleeding in Cirrhotic Patients With Portal Vein Thrombosis: A Randomized Controlled Trial
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- Sponsor
- Air Force Military Medical University, China · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
portal vein thrombosis may be a negative prognostic marker of variceal bleeding in liver cirrhosis. Compared with conventional endoscopic and pharmacological therapy, transjugular intrahepatic portosystemic shunt may further improve the outcomes of portal vein thrombosis in liver cirrhosis with variceal bleeding.
Detailed description
Portal vein thrombosis may be a negative prognostic marker of variceal bleeding in liver cirrhosis. Compared with conventional endoscopic and pharmacological therapy, transjugular intrahepatic portosystemic shunt may further improve the outcomes of portal vein thrombosis in liver cirrhosis with variceal bleeding. However, the safety of transjugular intrahepatic portosystemic shunt remains uncertain in patients with portal vein thrombosis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Transjugular intrahepatic portosystemic shunt | Transjugular intrahepatic portosystemic shunt refers to an interventional radiological procedure by placing a stent between portal vein and hepatic vein. No specific device was used in the Interventional field. |
| DRUG | Non-selective beta blockers | Non-selective beta blockers are the drugs for reducing the portal pressure. |
| PROCEDURE | Endoscopic therapy | Endoscopic therapy includes the endoscopic variceal band ligation |
| DRUG | Anticoagulation | Anticoagulation therapy includes heparin and warfarin. |
Timeline
- Start date
- 2017-07-09
- Primary completion
- 2024-12-31
- Completion
- 2024-12-31
- First posted
- 2015-06-30
- Last updated
- 2022-10-25
Locations
8 sites across 1 country: China
Source: ClinicalTrials.gov record NCT02485184. Inclusion in this directory is not an endorsement.