NCT02484508

Multi-center Clinical Study of Guli Capsules in the Treatment of Knee Osteoarthritis

A Randomized, Double Blind, Single Simulation, Parallel Controlled, Multi-center Clinical Study of Guli Capsules in the Treatment of Knee Osteoarthritis

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 220 (estimated)
• Sponsor: Guizhou Bailing Group Pharmaceutical Co Ltd · Industry
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Previous study showed that Guli capsule could suppress the adjuvant multiple arthritis; have inhibitory effect on carrageenan gelatinous and formaldehyde foot swelling; improve the symptom of osteoporosis patients; and improve pain and limited joint activities of rheumatoid patients. To further verify the clinical effect of Guli capsule in the treatment of knee osteoarthritis, the investigators perform this multi-center clinical study.

Detailed description

Guli capsule, an approved Chinese patent drug, its main indications are for rheumatism, rheumatoid arthritis. Previous study showed that Guli capsule could suppress the adjuvant multiple arthritis; have inhibitory effect on carrageenan gelatinous and formaldehyde foot swelling; improve the symptom of osteoporosis patients; and improve pain and limited joint activities of rheumatoid patients. To further verify the clinical effect of Guli capsule in the treatment of knee osteoarthritis, the investigators perform this multi-center clinical study.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
DRUG	Guli capsule	Guli capsule,as the experimental drug,is taken 3 grains each time, 3 time per day
DRUG	Kangguzengsheng capsule	Kangguzengsheng capsule, as the active comparator, is taken 3 grains each time, 3 time per day

Timeline

• Start date: 2015-03-01
• Primary completion: 2016-03-01
• Completion: 2016-03-01
• First posted: 2015-06-29
• Last updated: 2015-06-29

Locations

1 site across 1 country: China