NCT02483741

The Use of Manuka Honey to Improve Healing After Third Molars Surgery

The Effect of Topical Application of Manuka Honey on Healing After Extraction of Impacted Lower Third Molars: A Split-Mouth Design Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Damascus University · Academic / Other
• Sex: All
• Age: 20 Years – 37 Years
• Healthy volunteers: Accepted

Summary

Since there is an evidence that Manuka honey is an antibacterial agent, the present study aims to confirm this characteristic and assess its effect in improving healing and reducing postsurgical symptoms, if topically applied after the surgical removal of impacted mandibular third molars

Detailed description

Sufficient evidence exists recommending the use of honey in the management of acute wounds and burns. Studies revealed that the healing effect of honey could be classified by its antibacterial, antiviral, anti-inflammatory and antioxidant properties of its components. Manuka honey has been shown to inhibit a wide range of microorganisms, including multiresistant strains. This unique honey is derived from flowers of manuka tree (Leptospermum scoparium) in New Zealand. Dihydroxyacetone and methylglyoxal are unique and naturally occurring constituents of manuka honey that correlate with its antibacterial activity. Since surgical extraction of impacted molars is one of the most common operations in the oral cavity and the postoperative symptoms disturbing the patient may reduce the quality of health service, this study aims to assess the healing potential of Manuka honey in reducing these symptoms by comparing the outcome of extraction of impacted lower molars with and without topical application of Manuka honey into the extraction socket.

Conditions

• Surgical Extraction of Impacted Third Molars

Interventions

Type	Name	Description
BIOLOGICAL	Manuka Honey	This material is going to be placed into the sockets of the extracted third molars in the experimental group

Timeline

• Start date: 2015-06-01
• Primary completion: 2016-05-01
• Completion: 2016-11-01
• First posted: 2015-06-29
• Last updated: 2016-12-07

Locations

1 site across 1 country: Syria