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Trials / Completed

CompletedNCT02483325

Study Evaluating the Efficacy of Allogeneic Transplant Conditioning With Adaptive Dose Busulfan Intravenous (Busilvex®) in Patients at High Risk of Carrying Blood Diseases

Phase II Study Evaluating the Efficacy of Allogeneic Transplant Conditioning With Adaptive Dose Busulfan Intravenous (Busilvex®) in Patients at High Risk of Carrying Blood Diseases

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
33 (actual)
Sponsor
Institut Paoli-Calmettes · Academic / Other
Sex
All
Age
55 Years
Healthy volunteers
Not accepted

Summary

Determine the efficiency of a myéloablative conditioning associating Fludarabine, Thymoglobuline, and intravenous Busulfan with adapted dose, according to a pharmacokinetics realized in the first day of administration (or J-6 of the conditioning) of the busulfan, in preparation for a allogenic transplant family or not family compatible HLA.

Conditions

Interventions

TypeNameDescription
DRUGAllogeneic transplant conditioningAllogeneic transplant

Timeline

Start date
2014-09-01
Primary completion
2018-03-01
Completion
2020-03-01
First posted
2015-06-26
Last updated
2019-01-24

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT02483325. Inclusion in this directory is not an endorsement.

Study Evaluating the Efficacy of Allogeneic Transplant Conditioning With Adaptive Dose Busulfan Intravenous (Busilvex®) (NCT02483325) · Clinical Trials Directory