NCT02480933

Silent Breast Cancer A Study of the Disease Prevalence Held by Imaging Guided Biopsies in Autopsy Specimens

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 768 (estimated)
• Sponsor: Centro Hospitalar Lisboa Ocidental · Other Government
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to define silent breast cancer prevalence in both sexes and will be held by biopsies performed in imaging suspicious areas of the breast (ecography and mammography) in cadavers without known breast cancer.

Detailed description

Cadavers of both sexes are going to be submitted to bilateral mastectomy. The specimens are going to be examined by palpation, ecography and mammography and all areas with (Breast Imaging Reporting and Data System) BI-RADS classification \>= 3 are going to be biopsied. Biopsy specimens are going to be processed by the pathology department and cancers are going to be identified and classified by their molecular type. The investigators intend to know which is the disease reservoir in various ages.

Conditions

• Female Breast Cancer
• Male Breast Cancer

Interventions

Type	Name	Description
PROCEDURE	Bilateral mastectomy	Bilateral mastectomy and imaging study of cadaveric breasts
OTHER	Biopsy	Biopsy of BI-RADS 3 and superior lesions

Timeline

• Start date: 2016-09-01
• Primary completion: 2020-09-01
• Completion: 2020-09-01
• First posted: 2015-06-25
• Last updated: 2017-11-28