NCT02480634

Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer

Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer: A Non-inferiority, Randomized, Open, Parallel and Controlled Prospective Clinical Study

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 280 (estimated)
• Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will give comparison of the bone pain remission and the adverse reaction of Zoledronic acid combine with High dose fractionation radiotherapy(30Gy/10f) and Zoledronic acid combine with low dose fractionation radiotherapy(15Gy/5f) . The purpose of this trial is to prove whether Zoledronic acid combine radiotherapy can reduce radiotherapy dose in treatment of non-small cell lung cancer bone metastasis'pain relief or not.

Detailed description

Further study details as provided by oncology center of Daping hospital

Conditions

• Non-small Cell Lung Cancer
• Bone Metastasis

Interventions

Type	Name	Description
DRUG	Zoledronic acid	Comparison the curative effect of the high does radiotherapy and low does therapy after use the Zoledronic acid
RADIATION	Radiotherapy	High dose：30Gy/10f Low dose：15Gy/5f

Timeline

• Start date: 2019-06-01
• Primary completion: 2021-09-01
• Completion: 2022-12-01
• First posted: 2015-06-24
• Last updated: 2019-01-16