NCT02480478

Serum Autotaxin Levels in Cholestasis of Pregnancy

Diagnostic Accuracy of Serum Autotaxin Levels in Cholestasis of Pregnancy

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Sisli Hamidiye Etfal Training and Research Hospital · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Intrahepatic cholestasis of pregnancy is the most common liver disease in pregnancy. It is is a pregnancy-specific liver disorder with onset mainly in the third trimester of pregnancy. ICP is characterized by pruritus, elevated serum fasting bile salts and transaminases and an increased risk of adverse fetal outcomes. Serum autotaxin levels were found highly sensitive and specific biomarker to to differentiate ICP from other pregnancy-related liver disorders or pruritic dermatoses. The purpose of the study is to determine the diagnostic accuracy of serum autotaxin activity in cholestasis of pregnancy.

Detailed description

Collected data will enable us to compare serum autotaxin levels in cholestasis of pregnancy and healthy control group.

Conditions

• Intrahepatic Cholestasis of Pregnancy

Timeline

• Start date: 2015-06-01
• Primary completion: 2016-06-01
• Completion: 2017-01-01
• First posted: 2015-06-24
• Last updated: 2016-04-20

Locations

1 site across 1 country: Turkey (Türkiye)