Clinical Trials Directory

Trials / Completed

CompletedNCT02472886

Safety and Efficacy of Ledipasvir/Sofosbuvir in Adults With Chronic HCV Infection

A Phase 3b, Multicenter, Open-Label Study to Evaluate the Safety and Efficacy of Ledipasvir/Sofosbuvir in Adults With Chronic HCV Infection

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
153 (actual)
Sponsor
Gilead Sciences · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The primary objectives of this study are to evaluate the antiviral efficacy, safety, and tolerability of ledipasvir/sofosbuvir (LDV/SOF) fixed dose combination (FDC) with or without ribavirin (RBV) in adults with chronic hepatitis C virus (HCV) infection.

Conditions

Interventions

TypeNameDescription
DRUGLDV/SOF90/400 mg FDC tablet administered orally once daily
DRUGRBVTablets administered orally in a divided daily dose according to package insert weight-based dosing recommendations (\< 75 kg = 1000 mg and ≥ 75 kg = 1200 mg)

Timeline

Start date
2015-06-17
Primary completion
2016-03-30
Completion
2016-06-30
First posted
2015-06-16
Last updated
2018-11-16
Results posted
2017-05-10

Locations

20 sites across 2 countries: Estonia, Russia

Regulatory

Source: ClinicalTrials.gov record NCT02472886. Inclusion in this directory is not an endorsement.