NCT02470962

Cardiac Involvement in Patients With Duchenne/Becker Muscular Dystrophy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 59 (actual)
• Sponsor: University Children's Hospital, Zurich · Academic / Other
• Sex: Male
• Age: 8 Years – 18 Years
• Healthy volunteers: Accepted

Summary

This study evaluates the function of the heart in young patients with muscular dystrophy type Duchenne or Becker. Participants have their hearts examined at regular intervals by ultrasound (echocardiography) and cardiac magnetic resonance imaging.

Detailed description

Muscular dystrophy leads to progressive loss of function in all muscles during childhood and adolescence, including the heart. The usual method to evaluate the heart is echocardiography, emphasizing few parameters. Cardiac magnetic resonance imaging is not as widely available as echocardiography, but early changes can be detected before they become visible on echocardiography. In this study, the investigators compare the methods of measuring heart function in order to find the best measurements for follow up and to see how fast the degenerative changes occur in the hearts of patients with muscular dystrophy.

Conditions

• Duchenne / Becker Muscular Dystrophy

Interventions

Type	Name	Description
OTHER	Observation	Observation by serial echocardiography with extended techniques and cardiac magnetic resonance imaging

Timeline

• Start date: 2015-06-01
• Primary completion: 2022-03-22
• Completion: 2022-03-22
• First posted: 2015-06-12
• Last updated: 2025-03-20

Locations

1 site across 1 country: Switzerland