NCT02467725

EnMotion, Embryo's Natural Motion

EnMotion, Embryo's Natural Motion: The Impact of Dynamic Culture on the Development of Useable Blastocysts

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Reproductive Medicine Associates of New Jersey · Academic / Other
• Sex: Female
• Age: 18 Years – 42 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to determine if a dynamic embryo microenvironment impacts embryo development and reproductive potential in comparison to static culture.

Detailed description

The proposed research design is a prospective randomized control trial. Patients with normal ovarian reserve, who would be expected to have reasonable outcomes after in vitro fertilization, will serve as the subjects. Embryos from the same patient will be randomized to either static or dynamic culture. They will then be cultured to the blastocyst stage of embryo development and biopsied for preimplantation genetic screening. The best chromosomally normal embryo from each culture group will be selected and transferred to complete a double embryo transfer in a subsequent frozen embryo transfer cycle the following month.

Conditions

• Infertility

Interventions

Type	Name	Description
OTHER	Dynamic culture platform	Patients will have their cohort of embryos split in half. Half will be cultured in the dynamic platform and the other half cultured in static.

Timeline

• Start date: 2015-06-09
• Primary completion: 2018-05-31
• Completion: 2018-10-15
• First posted: 2015-06-10
• Last updated: 2019-04-05

Locations

1 site across 1 country: United States