NCT02467634

Study of HUCNS-SC Subretinal Transplantation in Subjects With GA of AMD

A Phase II Proof-of-Concept Study of the Safety and Efficacy of HUCNS-SC Subretinal Transplantation in Subjects With Geographic Atrophy of Age-Related Macular Degeneration

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: StemCells, Inc. · Industry
• Sex: All
• Age: 50 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

A fellow eye controlled study of HUCNS-SC sub-retinal transplantation in subjects with bilateral GA AMD. All subjects will be assigned to HUCNS-SC transplantation.

Detailed description

A fellow eye controlled study of HUCNS-SC sub-retinal transplantation in subjects with bilateral geographic atrophy (GA) age-related macular degeneration (AMD). All subjects will be assigned to HUCNS-SC transplantation. All subjects will be followed for efficacy and safety for 12 months. An independent data monitoring committee (IDMC) will review adverse events for the duration of the study.

Conditions

• Age-Related Macular Degeneration

Interventions

Type	Name	Description
BIOLOGICAL	HuCNS-SC sub-retinal transplantation	HuCNS-SC sub-retinal transplantation in subjects with bilateral GA AMD

Timeline

• Start date: 2015-06-01
• Primary completion: 2016-05-01
• Completion: 2016-05-01
• First posted: 2015-06-10
• Last updated: 2016-06-02

Locations

12 sites across 1 country: United States