Trials / Unknown
UnknownNCT02464072
Subtotal Parathyroidectomy or Total Parathyroidectomy With Autograft in Chronic Kidney Disease Patients Under Dialysis
Randomized Clinical Trial of Subtotal Parathyroidectomy or Total Parathyroidectomy With Immediate Heterotopic Autograft in Chronic Renal Disease Patients Stage V Under Dialysis
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 133 (actual)
- Sponsor
- University of Sao Paulo General Hospital · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
This study evaluates the metabolic and clinical results of two well recognized and accepted surgical techniques in the management of severe hyperparathyroidism in patients under regular dialysis treatment.
Detailed description
Prospective randomized trial in the surgical management of severe hyperparathyroidism of chronic kidney disease stage V under dialysis. Patients will be randomized and they will be submitted to subtotal parathyroidectomy or total parathyroidectomy with immediate heterotopic autograft of 45 or 90 fragments of parathyroid tissue.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Subtotal Parathyroidectomy | Subtotal parathyroid resection leaving the estimated mass of two normal parathyroid glands in situ. The type of operation is the intervention. No new device or drug is involved. |
| PROCEDURE | Total Parathyroidectomy + 45 autografts | Immediate autograft of 45 fragments of parathyroid tissue, after a total parathyroidectomy.This type of operation is the standard intervention at the institution at the moment. No new device or drug is involved. |
| PROCEDURE | Total Parathyroidectomy + 90 autografts | Immediate autograft of 90 fragments of parathyroid tissue, after a total parathyroidectomy.The type of operation is the intervention. No new device or drug is involved. |
Timeline
- Start date
- 2012-07-01
- Primary completion
- 2024-01-01
- Completion
- 2024-01-01
- First posted
- 2015-06-08
- Last updated
- 2023-05-17
Locations
1 site across 1 country: Brazil
Source: ClinicalTrials.gov record NCT02464072. Inclusion in this directory is not an endorsement.