NCT02463669

The Use of Point-of-Care Ultrasound in the Diagnosis of Acute Infectious Mononucleosis in the Emergency Department

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 200 (actual)
• Sponsor: Jewish General Hospital · Academic / Other
• Sex: All
• Age: 10 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine if splenomegaly on point-of-care ultrasound (POCUS) is an accurate and user-friendly surrogate to the heterophile antibody test and Epstein-Barr Virus (EBV) serologies to diagnose acute mononucleosis infection in patients presenting with sore throat to the Emergency Department (ED).

Detailed description

The investigators seek to determine whether the presence of splenomegaly on POCUS can accurately diagnose acute infectious mononucleosis in symptomatic ED patients, and determine the feasibility of performing point-of-care ultrasound for splenomegaly by emergency physicians in the emergency department setting.

Conditions

• Infectious Mononucleosis
• Splenomegaly

Interventions

Type	Name	Description
DEVICE	Point-of-care ultrasound	Enrolled patients will undergo POCUS of the spleen by the treating emergency physician (resident, fellow or attending). Canadian Emergency Ultrasound Society (CEUS) certified residents, fellows and attending physicians will conduct the bedside ultrasonography after receiving specific training for the purposes of this study. The spleen will be assessed using a curved 2-6 Megahertz (MHz) transducer with the participant in the supine position. The cranio-caudal splenic length will be measured and its maximum dimension will be recorded on the standardized study data sheet.

Timeline

• Start date: 2016-04-01
• Primary completion: 2020-10-04
• Completion: 2020-10-04
• First posted: 2015-06-04
• Last updated: 2020-10-06

Locations

2 sites across 1 country: Canada