NCT02462902

Comparison And Outcomes Of Fluid Resucitation With 0.9% Normal Saline And 5% Albumin In Cirrhosis Patients With Sepsis Induced Hypotension

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 308 (actual)
• Sponsor: Institute of Liver and Biliary Sciences, India · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

300 consecutive patients with cirrhosis of any aetiology admitted with features of sepsis and sepsis induced hypotension to the intensive care unit, the emergency department and the step down units of Institute of Liver and Biliary Sciences, New Delhi, who fulfil the inclusion criteria. This study will be a single centre prospective randomized comparative trial. Patients will be randomized into two groups. Group A will receive crystalloid, 0.9% sodium chloride solution (total of 30ml/kg over 30 minutes) and Group B will receive colloid, 5% albumin (250 ml over 15 minutes).

Conditions

• Cirrhosis With Septic Shock

Interventions

Type	Name	Description
DRUG	5% albumin Infusion	colloid, 5% albumin (250 ml over 15 to 30 minutes).
DRUG	0.9% sodium chloride solution	0.9% sodium chloride solution (total of 30ml/kg over 15 to 30 minutes)

Timeline

• Start date: 2014-02-01
• Primary completion: 2015-06-01
• Completion: 2015-06-01
• First posted: 2015-06-04
• Last updated: 2015-12-30

Locations

1 site across 1 country: India