Clinical Trials Directory

Trials / Completed

CompletedNCT02461771

Assessment of Safety, Tolerability and Pharmacokinetics of Intravitreal Pegcetacoplan (APL-2) for Patients With Wet AMD

Assessment of Safety, Tolerability and Pharmacokinetics of Intravitreal APL-2 Therapy for Neovascular Age-Related Macular Degeneration (AMD)

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
13 (actual)
Sponsor
Apellis Pharmaceuticals, Inc. · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

The objective of this study is to provide initial safety, tolerability and pharmacokinetics information of intravitreal administration of pegcetacoplan in order to support further development into larger Phase II studies for treatment of patients with AMD.

Conditions

Interventions

TypeNameDescription
DRUGPegcetacoplanOn treatment day, subjects will be administered a single 100 μL IVT injection of pegcetacoplan at the dose corresponding to their treatment assignment.

Timeline

Start date
2015-01-28
Primary completion
2016-03-08
Completion
2016-03-08
First posted
2015-06-03
Last updated
2020-10-06
Results posted
2020-10-06

Locations

4 sites across 2 countries: United States, Australia

Source: ClinicalTrials.gov record NCT02461771. Inclusion in this directory is not an endorsement.