NCT02460471

Palliative Radiotherapy Protocol in Head and Neck Cancer

Palliative Radiotherapy for Advanced Head and Neck Carcinomas, a Phase II Study

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Maisonneuve-Rosemont Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Phase II prospective study or Palliative Radiotherapy of 25 Gy in 5 fractions, Intensity Modulated, for frail patients with incurable head and neck cancer. Comprehensive Quality of life (QLQ-C30, head and neck module, QLQ C15 PAL) and toxicity data (CTCAE v 4.0) collected.

Detailed description

Patients deemed too frail for radical treatment or incurable because of tumour extension, as determined by an experienced tumour board, were eligible for this study of palliative radiotherapy delivered by intensity modulation, 25 Gy in 5 daily fractions over one week. This study was conducted in two academic centers.

Conditions

• Head and Neck Neoplasms
• Quality of Life

Interventions

Type	Name	Description
RADIATION	palliative radiation therapy	thermoplastic mask immobilization. CT in treatment position. radiation dose of 25 Gy in 5 daily fractions over one week 6 MV photons by intensity modulation. Target volume is the symptomatic tumour volume with a 5 mm margin

Timeline

• Start date: 2011-06-01
• Primary completion: 2015-04-01
• Completion: 2015-04-01
• First posted: 2015-06-02
• Last updated: 2015-06-02

Locations

2 sites across 1 country: Canada