NCT02457416

Take Away Food Allergy; Inducing Tolerance in Children Allergic to Peanut

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 77 (actual)
• Sponsor: Oslo University Hospital · Academic / Other
• Sex: All
• Age: 5 Years – 15 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to identify prognostic markers and possible success rate of tolerance induction to peanut allergens in children allergic to peanut.

Detailed description

The study is an open randomized controlled study on oral immunotherapy including 60 children (40 on active treatment, 20 controls) with primary peanut allergy. The study has 4 phases: 1: inclusion/randomization including a double blind placebo controlled food Challenge 2: bi weekly up-dosing to maintenance dose after 48 weeks, 3: maintenance period of 3 years 4: 1 year follow up after end of treatment. Clinical parameters as well as immunological (serological and cellular) will be recorded at inclusion, after 3 months of up-dosing, at end of up-dosing, after 1 and 3 years of maintenance treatment and after 3 and 12 year of follow up.

Conditions

• Food Hypersensitivity

Interventions

Type	Name	Description
OTHER	Peanut	Treatment with peanut in increasing doses until a maintenance dose

Timeline

• Start date: 2014-03-01
• Primary completion: 2019-03-01
• Completion: 2019-03-01
• First posted: 2015-05-29
• Last updated: 2016-05-04

Locations

1 site across 1 country: Norway