NCT02455518

Comparative Efficacy of 4 Oral Analgesics

Comparative Efficacy of 4 Oral Analgesics for the Initial Management of Acute Musculoskeletal Extremity Pain

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 416 (actual)
• Sponsor: Montefiore Medical Center · Academic / Other
• Sex: All
• Age: 21 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to perform a randomized, double blind 4-arm clinical trial of the comparative efficacy of 4 oral analgesics in the initial management of acute musculoskeletal extremity pain presenting to the ED.

Detailed description

To perform a randomized, double blind 4-arm clinical trial of the comparative efficacy of 4 oral analgesics in the initial management of acute musculoskeletal extremity pain presenting to the ED. The 4 groups are as follows: 1. Oxycodone/acetaminophen (5/325) 2. Hydrocodone/acetaminophen (5/325) 3. Codeine/acetaminophen (30/300) 4. Ibuprofen/acetaminophen (400/1000)

Conditions

• Pain

Interventions

Type	Name	Description
DRUG	Oxycodone/acetaminophen
DRUG	Hydrocodone/acetaminophen
DRUG	Codeine/acetaminophen
DRUG	Ibuprofen/acetaminophen

Timeline

• Start date: 2015-07-01
• Primary completion: 2016-08-01
• Completion: 2017-10-04
• First posted: 2015-05-28
• Last updated: 2018-02-13
• Results posted: 2018-02-13

Locations

1 site across 1 country: United States