NCT02454829

Follow-up of Ovarian Function in Young Women Who Underwent Ovarian Cortex Cryopreservation

Follow-up of Ovarian Function in Young Girls and Women Who Underwent Ovarian Cortex Cryopreservation for Fertility Preservation at the Cliniques Universitaires Saint-Luc

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 546 (actual)
• Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

Evaluation of ovarian function by a questionnaire and by medical file analysis of women and girls who underwent ovarian cortex cryopreservation for fertility preservation between 1997 an 2013 in the investigators' institution in order to evaluate their residual ovarian function. A second part of the questionnaire concerns these women's satisfaction regarding the procedure.

Detailed description

Between 1997 and december 2013, 546 girls and women underwent ovarian cortex cryopreservation in the investigators' institution for fertility preservation. The main indications were the need for a gonadotoxic treatment, repeated ovarian surgery and a genetic risk for premature ovarian failure . These women will be sent a questionnaire concerning their ovarian function since the procedure and a questionnaire about their satisfaction concerning the procedure. Six different questionnaires will be used adapted to the patient's initial indication for cryopreservation and the patient's age at the time of cryopreservation. Complementary data will be obtained by medical file analysis and by contacting the patient's family doctor or gynecologist. Data will be correlated with received gonadotoxic treatment and surgical interventions. The purpose of the study is to improve the indications and patient selection for ovarian cortex cryopreservation.

Conditions

• Female Infertility

Interventions

Type	Name	Description
OTHER	questionnaire	A questionnaire will be send concerning the patient's ovarian function since the cryopreservation procedure i.e: progression of puberty, menstrual cycle, hormonal treatment, desire for pregnancy, occurence of pregnancy, details of pregnancy, need for ART (Artificial Reproductive Techniques), and about the patient's satisfaction concerning the cryopreservation procedure. Data collected will be correlated with treatments received.

Timeline

• Start date: 2015-03-01
• Primary completion: 2016-01-01
• Completion: 2016-01-01
• First posted: 2015-05-27
• Last updated: 2016-04-15

Locations

1 site across 1 country: Belgium