NCT02453126

Fibrostenotic Eosinophilic Esophagitis: Assessment Tools

Fibrostenotic Eosinophilic Esophagitis: Endoscopic, Histologic and Molecular Characterization and Evaluation of Clinical Assessment Tools

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 250 (estimated)
• Sponsor: University of Colorado, Denver · Academic / Other
• Sex: All
• Age: 5 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

This protocol addresses a central hypothesis that fibrostenotic Eosinophilic Esophagitis (EoE) is characterized by abnormal esophageal structure and compliance compared to non fibrostenotic EoE and that distinctive cellular and molecular profiles predict the fibrostenotic phenotype. This study aims to define and assess the changes that occur in the structure and dynamics of the esophageal wall in pediatric Eosinophilic Esophagitis along with characterizing the histologic and molecular patterns in fibrostenotic EoE.

Conditions

• Eosinophilic Esophagitis

Timeline

• Start date: 2014-12-01
• Primary completion: 2024-06-01
• Completion: 2024-06-01
• First posted: 2015-05-25
• Last updated: 2024-02-05

Locations

1 site across 1 country: United States