Clinical Trials Directory

Trials / Completed

CompletedNCT02451943

A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue Sarcoma

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Doxorubicin Plus Olaratumab Versus Doxorubicin Plus Placebo in Patients With Advanced or Metastatic Soft Tissue Sarcoma

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
509 (actual)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The main purpose of this study is to evaluate the efficacy of the combination of doxorubicin plus the study drug known as olaratumab versus doxorubicin plus placebo in participants with advanced or metastatic soft tissue sarcoma.

Conditions

Interventions

TypeNameDescription
DRUGOlaratumabAdministered IV
DRUGDoxorubicinAdministered IV
DRUGPlaceboAdministered IV

Timeline

Start date
2015-09-14
Primary completion
2018-12-05
Completion
2024-06-27
First posted
2015-05-22
Last updated
2025-07-15
Results posted
2019-12-17

Locations

114 sites across 25 countries: United States, Argentina, Australia, Austria, Belgium, Brazil, Canada, Denmark, Finland, France, Germany, Hungary, Israel, Italy, Japan, Mexico, Netherlands, Poland, Russia, South Korea, Spain, Sweden, Switzerland, Taiwan, United Kingdom

Source: ClinicalTrials.gov record NCT02451943. Inclusion in this directory is not an endorsement.