NCT02450474

Mobilising Lower Limb Fluid for Hemodynamic Stability in Haemodialysis

Pilot Evaluation of Intermittent Pneumatic Compression and Neuromuscular Electrical Stimulation for Enhancing Vascular Refilling in Haemodialysis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (estimated)
• Sponsor: The Leeds Teaching Hospitals NHS Trust · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Cardiovascular disease is the leading cause of death of dialysis patients and poor fluid management is associated with the increased risk. One of the principal limitations in avoiding chronic fluid overload in this patient group is the refilling rate the rate at which fluid is transferred from tissues into the vascular system. If this rate cannot match the prescribed rate of fluid removal during dialysis the patient will end up with chronic fluid overload. Two proposed methods of increasing the rate of refilling are intermittent pneumatic compression (IPC) devices, which increase the pressure of the fluid in tissue, and neuromuscular electrical stimulation (NMES) which activates the muscle pump and lymphatic drainage. This investigation will trial the use of these two methods in patients suspected of having inadequate refilling rates. Outcome measures will be based on fluid status, presence of oedema and quality of life.

Conditions

• Kidney Failure

Interventions

Type	Name	Description
DEVICE	Intermittent pneumatic compression device	Flowtron, Circulation Booster and Sports XL devices will be used.
DEVICE	Neuromuscular electrical stimulation	Flowtron, Circulation Booster and Sports XL devices will be used.

Timeline

• Start date: 2014-02-01
• Primary completion: 2016-01-01
• Completion: 2016-01-01
• First posted: 2015-05-21
• Last updated: 2015-05-21

Locations

1 site across 1 country: United Kingdom