NCT02450279

Scintigraphic Comparison of Lung Deposition With Two Nebulizers During Invasive Mechanical Ventilation

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Many devices are available for nebulising drug solution during invasive mechanical ventilation. Vibrating-mesh nebulizers ensure the highest lung deposition output. A recent international survey on aerosol therapy during mechanical ventilation (Ehrmann et al. 2013) reported that jet nebulizers remained the mostly used. The aim of this study is to compare lung deposition of a radiolabeled administered with both nebulizers during invasive mechanical ventilation by planar scintigraphy.

Conditions

• Post-operative Neurosurgery

Interventions

Type	Name	Description
DRUG	technetium-99m - Diethylenetriaminepentaacetic acid
DEVICE	Vibrating-mesh nebulizer
DEVICE	Jet Nebulizer
OTHER	Planar scintigraphy
OTHER	Preoperative spirometry

Timeline

• Start date: 2016-03-01
• Primary completion: 2017-11-07
• First posted: 2015-05-21
• Last updated: 2017-11-08

Locations

1 site across 1 country: Belgium