Trials / Completed
CompletedNCT02442232
Hemodynamic Changes After Anesthesia With Propofol: Study of Biomarkers
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 65 (actual)
- Sponsor
- Conselho Nacional de Desenvolvimento Científico e Tecnológico · Other Government
- Sex
- All
- Age
- 40 Years – 80 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to evaluate biomarkers affecting the hemodynamic responses to propofol. Particularly, the investigators will assess the effects of polymorphisms in NOS3 and PRKCA genes on hemodynamic responses to propofol and the effects of these polymorphisms on biomarkers related to nitric oxide after propofol anesthesia. In addition, the investigators will evaluate the effects of propofol anesthesia on biomarkers related to nitric oxide in hypertensive patients chronically treated with angiotensin-converting enzyme inhibitors.
Conditions
Timeline
- Start date
- 2015-08-01
- Primary completion
- 2015-12-01
- Completion
- 2016-05-01
- First posted
- 2015-05-13
- Last updated
- 2016-08-26
Source: ClinicalTrials.gov record NCT02442232. Inclusion in this directory is not an endorsement.