NCT02438735

Endometrioma Related Reduced Ovarian Reserve

The Effect Of The Presence Of Endometriomas On Ovarian Reserve

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 80 (actual)
• Sponsor: Uludag University · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Prior studies have shown surgical excision of endometriomas are associated with a decline in ovarian reserve as assessed by serum anti-Mullerian Hormone (AMH) levels. However, the natural history of serum AMH levels in the presence of untreated endometriomas are unknown. Purpose of this study is to determine whether the presence of endometriomas cause a faster decline in serum AMH levels than in healthy women over a six months period.

Detailed description

The study is a prospective cohort study. Women diagnosed with endometriomas by transvaginal or transabdominal ultrasound or MRI will be recruited from a tertiary care endometriosis clinic. Age matched healthy controls will be recruited from the staff of the same hospital. A priorly published historical group of women who underwent endometrioma excision will be a second comparator.

Conditions

• Endometriosis

Interventions

Type	Name	Description
PROCEDURE	laparoscopic endometrioma excision
OTHER	Conservative follow up

Timeline

• Start date: 2015-04-01
• Primary completion: 2017-08-01
• Completion: 2017-08-01
• First posted: 2015-05-08
• Last updated: 2017-12-19

Locations

1 site across 1 country: Turkey (Türkiye)