NCT02435771

Efficacy Of Ergocalciferol In Adults According To BMI

• Status: Terminated
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 44 (actual)
• Sponsor: Walter Reed National Military Medical Center · Federal
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Vitamin D insufficiency is an increasing trend in the United States. According to the NHANES data collection there was a near doubling of patients with vitamin D deficiency in 10 years. Vitamin D deficiency is associated with several adverse outcomes such as increased fractures, certain microbial diseases, cardiovascular diseases, and metabolic dysfunction. The increasing prevalence of vitamin D deficiency has been attributed to the increasing prevalence of obesity. Several studies have shown that obese patients have lower 25-OH vitamin D (25-OHD) levels compared to nonobese patients and obese patients require more vitamin D compared to nonobese patients. The most commonly prescribed medication to replete vitamin D deficiency is oral ergocalciferol. To date, no prospective trials have been published to evaluate a standard protocol in the treatment of vitamin D insufficiency in adults.

Conditions

• Obesity
• Vitamin D Deficiency

Interventions

Type	Name	Description
DRUG	Ergocalciferols	Treatment 1- 400,000 IU
DRUG	Ergocalciferols	Treatment 2- 800,000 IU

Timeline

• Start date: 2011-07-01
• Primary completion: 2017-04-01
• Completion: 2017-04-01
• First posted: 2015-05-06
• Last updated: 2017-05-11

Locations

1 site across 1 country: United States