NCT02435225

Brain Connectivity and Mindfulness Training in Youth With Bipolar Disorder Not Otherwise Specified (NOS)

Brain Connectivity and Mindfulness Training in Youth With Bipolar Disorder NOS

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 13 Years – 17 Years
• Healthy volunteers: Accepted

Summary

The investigators propose to study 30 adolescents with bipolar disorder, not otherwise specified (BD NOS) and a family history of Bipolar I Disorder (BD) at baseline with rs-fMRI (functional magnetic resonance imaging) and functional connectivity (FC) analyses and compare data with previously acquired rs-fMRI and FC data from 20 age- and gender-matched healthy controls (HC). Subjects will then undergo a 12-week Mindfulness based stress reduction- teen (MBSR-T) intervention and be reassessed and rescanned. The intervention and scanning will take place in groups of 6-8 subjects/group/year over the 4 years. This proposal will be a natural progression of past research, while extending the investigators' expertise to include advanced FC analyses and mindfulness based interventions in youth with mood dysregulation. The investigators will also integrate trainees into the imaging and therapy components of this study, furthering our mission of mentoring the next generation of innovative researchers who will push the field forward.

Conditions

• Bipolar Disorder, NOS

Interventions

Type	Name	Description
BEHAVIORAL	Mindfulness Based Stress Reduction for Teens Group	A 12-Week weekly group intervention to train adolescents in mindfulness practice

Timeline

• Start date: 2014-05-01
• Primary completion: 2014-06-01
• Completion: 2017-09-01
• First posted: 2015-05-06
• Last updated: 2018-07-19

Locations

1 site across 1 country: United States