Trials / Completed
CompletedNCT02434562
Development and Validation of in Vitro Cell-based Bioassays for Nuclear Receptor Activation
Development and Validation of in Vitro Cell-based Bioassays for Nuclear Receptor Activation by Human Serum
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 73 (actual)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
This is a prospective biobank set up to collect serum from patients with disorders associated with changes in androgens, estrogens or sex hormone-binding globulin (SHBG), before and/or after treatment.
Detailed description
In vitro cell-based bioassays may be a technique to measure serum androgen or estrogen bioactivity. In this study investigators are collecting serum (and if possible, urine) samples from different cohorts of patients, before and/or after treatment. The aim is to measure androgens, estrogens and SHBG as well as in vitro bioactivity with newly developed cell-based bioassays, and to compare different techniques to each other as well as to clinical endpoints available in the patient's Electronic Health Record.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Serum (with or without urine) samples |
Timeline
- Start date
- 2012-04-01
- Primary completion
- 2016-09-01
- Completion
- 2016-09-30
- First posted
- 2015-05-05
- Last updated
- 2017-01-25
Source: ClinicalTrials.gov record NCT02434562. Inclusion in this directory is not an endorsement.