Clinical Trials Directory

Trials / Terminated

TerminatedNCT02433158

Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease

An Open-Label Extension Study to Evaluate the Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
154 (actual)
Sponsor
GlycoMimetics Incorporated · Industry
Sex
All
Age
6 Years
Healthy volunteers
Not accepted

Summary

This is an open label extension study in subjects with Sickle Cell Disease (SCD) who have completed the double blind Phase 3 study (B5201002).

Detailed description

This is an open label extension study in subjects who are 6 years of age or older with Sickle Cell Disease (SCD) who have completed the double blind Phase 3 study (B5201002). This study is designed to evaluate the safety and describe the efficacy of rivipansel as treatment for one or more vaso-occlusive crisis (VOC) events in hospitalized subjects with SCD.

Conditions

Interventions

TypeNameDescription
DRUGRivipanselRivipansel will be infused intravenously every 12 hours up to a maximum of 15 doses.

Timeline

Start date
2015-12-16
Primary completion
2019-11-15
Completion
2019-11-15
First posted
2015-05-04
Last updated
2021-02-10

Locations

97 sites across 2 countries: United States, Canada

Regulatory

Source: ClinicalTrials.gov record NCT02433158. Inclusion in this directory is not an endorsement.