Clinical Trials Directory

Trials / Terminated

TerminatedNCT02432690

A Study of BBI503 in Asymptomatic Recurrent Ovarian Cancer Patients With CA-125 Elevation

A Phase II Clinical Study of BBI503 in Asymptomatic Recurrent Ovarian Cancer Patients With CA-125 Elevation

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
13 (actual)
Sponsor
Sumitomo Pharma America, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This was an open-label, single-arm, Phase II study in which amcasertib (BBI503) was administered to adult, asymptomatic patients with recurrent ovarian cancer who had elevated CA-125.

Conditions

Interventions

TypeNameDescription
DRUGBBI503BBI503 will be administered orally, once daily. Dosing will begin at 200 mg once daily, preferably at bedtime and 2 hours after a meal. Dose modification in case of adverse events is allowed according to the schedule below; Full dose: 200 mg daily, Modification Level-1: 100 mg daily, Modification Level-2: 50 mg daily.

Timeline

Start date
2015-06-01
Primary completion
2017-01-02
Completion
2017-01-02
First posted
2015-05-04
Last updated
2023-11-15
Results posted
2022-08-29

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02432690. Inclusion in this directory is not an endorsement.