NCT02430090

Comparison of Intratechal Levobupivacaine and Adding With Sufetanil and Fentanyl in Ceserean Section

Comparison of Intratechal Low-Dose Levobupivacaine With Levobupivacaine-Fentanyl and Levobupivacaine-Sufentanil Combinations for Cesarean Section

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: Ankara City Hospital Bilkent · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

45 pregnant women undergoing cesarean section were enrolled in the study in november 2006 to march 2007. 2 ml of 0.5% levobupivacaine was added to 1 ml of saline in group I, 1 ml of 15 µcg of fentanyl in group II and 1 ml of 1,5 µcg sufentanil in group III by intratechal administration. Hemodynamic parameters, characteristics of sensory and motor blockade, peri-operative and postoperative visual analogue scale (VAS) pain scores, the time to the first analgesic requirement and adverse effects were recorded.

Detailed description

45 pregnant women undergoing cesarean section were enrolled in the study in november 2006 to march 2007. Using CSE technique, 2 ml of 0.5% levobupivacaine was added to 1 ml of saline in group I, 1 ml of 15 µcg of fentanyl in group II and 1 ml of 1,5 µcg sufentanil in group III by intratechal administration. Hemodynamic parameters, characteristics of sensory and motor blockade, peri-operative and postoperative visual analogue scale (VAS) pain scores, the time to the first analgesic requirement and adverse effects were recorded.

Conditions

• Anesthesia

Interventions

Type	Name	Description
DRUG	Levobupivacaine	this used in intratechal area and for spinal anesthesia in ceserean section
DRUG	Fentanyl	this used in intratechal area and for spinal anesthesia in ceserean section
DRUG	Sufentanil	this used in intratechal area and for spinal anesthesia in ceserean section
DRUG	Levobupivacaine	this used in intratechal area and for spinal anesthesia in ceserean section
DRUG	Levobupivacaine	this used in intratechal area and for spinal anesthesia in ceserean section

Timeline

• Start date: 2006-11-01
• Primary completion: 2007-03-01
• Completion: 2007-03-01
• First posted: 2015-04-30
• Last updated: 2021-11-19
• Results posted: 2015-06-10