NCT02429219

Saline With Alcohol in TransUrethral Resection aNd Photoselective Vaporisation of the Prostate

Prospective Study of Monitoring the Alcohol Concentration in Breathing Air During Transurethral Prostate Resection of Benign Prostate Hyperplasia (BPH) Assessing the Uptake of Irrigation Fluids

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: University of Magdeburg · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Not accepted

Summary

Transurethral therapy (TURiS / PVP) of benign prostatic hyperplasia (BPH) using an ethanol-containing saline irrigating fluid, prospective detected by breath alcohol measurement.

Detailed description

Aim was to evaluate the amount of absorbed saline irrigation fluid during transurethral therapy of benign prostatic hyperplasia (BPH). We want to differentiate two different methods of the surgical therapy: the TransUrethral Resection in Saline (TURiS) and the Photoselective Vaporisation of the Prostate (PVP). Both methods using saline irrigation. To measure the amount of absorbed saline irrigation fluid, we added pure Ethanol to the Irrigation fluid resulting in am 0,02% ethanol containing saline irrigation fluid. The conventional TransUrethral Resection of the Prostate (TUR) method is using electrolyte free irrigation. In the literature this method is well known for the occurence of the transurethral resection syndrome ("TUR syndrome"). This is caused by absorption of electrolyte-free irrigating fluid, followed by a hyponatraemic hyperhydration, and consists of symptoms from the circulatory and nervous Systems.

Conditions

• Benign Prostatic Hypertrophy

Interventions

Type	Name	Description
DRUG	Saline Irrigation with Ethanol	Saline Irrigation with Ethanol (alcohol)
PROCEDURE	transurethral resection of the prostate	transurethral electro-resection of the prostate (TURP)
PROCEDURE	photoselective vaporisation of the prostate	photoselective laser-vaporisation of the prostate (PVP)

Timeline

• Start date: 2013-11-01
• Primary completion: 2015-02-01
• Completion: 2015-02-01
• First posted: 2015-04-29
• Last updated: 2015-04-29

Locations

1 site across 1 country: Germany