NCT02426008

Improving Embryogenesis by Adding Growth Factors to In Vitro Human Culture Media

Growth Factors Supplementation to Single-Step Culture Medium

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 426 (actual)
• Sponsor: Ibn Sina Hospital · Other Government
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

The investigators suppose that adding growth factors that had been found in the female tubal fluid and uterus to In Vitro single step culture media for human embryos might improve the the embryogenesis In Vitro and the clinical outcome of the resulting off spring.

Detailed description

The IVF culture media design and upgrade underwent many ideas during the last 3 decades, we suppose that adding growth factors ( Insulin-like growth factor I, Insulin-like growth factor II, transforming growth factor-beta and epidermal growth factor ) as a promoting growth factors to Lifeglobal culture media might improve embryo development in vitro so we decide to design a trial to compare the embryogenesis by sibling Oocytes of the same patient between to arm of the same culture media and the same culture condition but with one arm with growth factors and the other is traditional one and closely monitor the outcome within the 2 arms and record the results.

Conditions

• In Vitro Human Embryo Development

Interventions

Type	Name	Description
OTHER	Growth Factors and Cytokine adding to embryo culture media
OTHER	No Intervention	Nothing to Add

Timeline

• Start date: 2015-05-01
• Primary completion: 2016-03-01
• Completion: 2016-03-01
• First posted: 2015-04-24
• Last updated: 2018-10-02

Locations

1 site across 1 country: Egypt