NCT02421380

Characterization of Hyperpolarized Pyruvate MRI Reproducibility

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 109 (estimated)
• Sponsor: Memorial Sloan Kettering Cancer Center · Academic / Other
• Sex: All
• Age: 21 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to test a new approach to see if the test results can be reproduced each time the Magnetic resonance imaging (MRI) is done for an individual patient. The study will explore the use of an imaging agent called hyperpolarized \[1-13C\] pyruvate (HP) with MRI scans. (MRI) is a technique that takes pictures of the body's organs using a magnetic field and radiofrequency waves that cannot be felt. In order to accomplish the goal of the study the patient will have two hyperpolarized MRI scans to assess if scans can be reproduced. The hyperpolarized MRI scans will be compared with the pathological results of the surgery to see if the hyperpolarized MRI provides additional information regarding disease metabolism.

Conditions

• Malignant Solid Tumors

Interventions

Type	Name	Description
DRUG	Hyperpolarized Pyruvate

Timeline

• Start date: 2015-04-01
• Primary completion: 2026-04-01
• Completion: 2026-04-01
• First posted: 2015-04-20
• Last updated: 2025-11-06

Locations

2 sites across 1 country: United States