Clinical Trials Directory

Trials / Completed

CompletedNCT02421172

Efficacy, Safety, and Pharmacokinetics Study of CJM112 in Hidradenitis Suppurativa Patients

A Randomized, Double-blind, Placebo Controlled, Multiple Dose Study to Evaluate the Clinical Efficacy, Safety, Tolerability, Dose Relation, Pharmacokinetics and Pharmacodynamics of CJM112 in Moderate to Severe Chronic Hidradenitis Suppurativa Patients

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
66 (actual)
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
Healthy volunteers
Not accepted

Summary

This is a randomized, double blind, multicenter study in patients with moderate to severe chronic hidradenitis suppurativa in parallel groups, to determine the efficacy and safety of multiple doses of CJM112 in comparison to placebo. The study has two periods to explore preliminary dose effects.

Conditions

Interventions

TypeNameDescription
BIOLOGICALCJM112CJM112 Fully human IgG1 monoclonal antibody
DRUGPlacebo

Timeline

Start date
2015-04-13
Primary completion
2016-11-23
Completion
2016-11-23
First posted
2015-04-20
Last updated
2022-07-13
Results posted
2019-05-23

Locations

16 sites across 5 countries: United States, Denmark, Germany, Netherlands, Switzerland

Regulatory

Source: ClinicalTrials.gov record NCT02421172. Inclusion in this directory is not an endorsement.