Clinical Trials Directory

Trials / Completed

CompletedNCT02418494

Health-Related Symptom Questionnaires in Measuring Quality of Life in HIV-Infected Participants Treated or Monitored for Anal Lesions

Development of a Health-Related Symptom Index for Persons Diagnosed With and Either Treated or Monitored for Anal High-Grade Squamous Intraepithelial Lesions (HSIL)

Status
Completed
Phase
Study type
Observational
Enrollment
85 (actual)
Sponsor
AIDS Malignancy Consortium · Network
Sex
All
Age
35 Years
Healthy volunteers
Not accepted

Summary

This research trial studies health-related symptom questionnaires in measuring quality of life in human immunodeficiency virus (HIV)-infected participants treated with or monitored for anal lesions. Collecting information and symptoms from patients diagnosed with anal lesions may help reduce the risk of anal cancer.

Detailed description

PRIMARY OBJECTIVES: I. To develop an Anal Cancer/HSIL Outcomes Research Study (ANCHOR) high-grade squamous intraepithelial lesion (HSIL) health-related quality of life (HRQoL) Index (HQI) using state-of-the-art measure development methodology that captures the most important HRQoL symptoms and concerns of those persons diagnosed with anal HSIL and either treated or untreated for anal HSIL. OUTLINE: Participants complete the ANCHOR HSIL HRQoL interview over 45-60 minutes, comparing the list of symptoms, concerns, or HRQOL impacts related to HSIL diagnosis and treatment. Some patients also complete a cognitive interview for up to 3 sessions.

Conditions

Interventions

TypeNameDescription
OTHERConcept ElicitationComplete cognitive interview to elicit relevant HSIL symptoms, compare to study index of symptoms, and rank symptoms in relation to effect on health-related quality of life
OTHERComprehension AssessmentComprehension assessment of draft quality of life assessment

Timeline

Start date
2015-04-01
Primary completion
2016-05-01
Completion
2016-05-01
First posted
2015-04-16
Last updated
2016-06-09

Locations

6 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT02418494. Inclusion in this directory is not an endorsement.