Clinical Trials Directory

Trials / Completed

CompletedNCT02415842

A Laboratory Evaluation of the Humoral Immune Response in Adults and Children to the H1 Hemagglutinin (HA) Stalk Domain and Other Influenza A Virus Protein Epitopes, After Administration of GlaxoSmithKline (GSK) Biologicals' Pandemic Influenza Vaccines

An Exploratory, Retrospective Laboratory Evaluation of the Humoral Immune Response in Adults and Children to the H1 HA Stalk Domain and Other Influenza A Virus Protein Epitopes, After Administration of GSK Biologicals' Pandemic Influenza Vaccines

Status
Completed
Phase
Study type
Observational
Enrollment
414 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
6 Months – 64 Years
Healthy volunteers
Accepted

Summary

The purpose of this exploratory, retrospective laboratory study is to assess the humoral immune response to H1 hemagglutinin stalk domain and other influenza A virus protein epitopes following administration, in adults and children, of GSK Biologicals' adjuvanted and unadjuvanted pandemic influenza vaccines, using archived serum samples from previously completed clinical trials.

Conditions

Interventions

TypeNameDescription
OTHERSerum samplesThe archived sera samples collected in previously completed pandemic influenza vaccine clinical trials (H1N1, H5N1, and H9N2 pandemic vaccines in adult trials and H5N1 pandemic vaccine in a pediatric trial) will be tested in this study.

Timeline

Start date
2015-10-26
Primary completion
2018-02-16
Completion
2018-02-16
First posted
2015-04-14
Last updated
2019-07-23
Results posted
2019-06-28

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02415842. Inclusion in this directory is not an endorsement.