Trials / Completed
CompletedNCT02415374
Bioavailability and Metabolism of Avenanthramide: a Novel Oat Phytochemical
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 16 (actual)
- Sponsor
- PepsiCo Global R&D · Industry
- Sex
- All
- Age
- 20 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
The purpose of the study is to examine whether orally ingested oat avenanthramides (AVA) in oat flour cookies are bioavailable in humans by measuring plasma and urine concentrations of AVAs and their potential metabolites after ingestion. The blood and urine concentrations will be quantified at several different time points after the oat flour cookies are consumed to characterize the "concentration-time profile".
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Avenanthramides | AVAs are a group of diphenolic acids that are found only in oats (Avena sativa). In this study, each dietary group of subjects will receive three cookies made with oat flour containing high-AVA (H-AVA, 229.56 mg/kg) and low-AVA (L-AVA, 32.69 mg/kg). |
Timeline
- Start date
- 2015-01-05
- Primary completion
- 2015-07-15
- Completion
- 2015-07-15
- First posted
- 2015-04-14
- Last updated
- 2021-03-10
Source: ClinicalTrials.gov record NCT02415374. Inclusion in this directory is not an endorsement.