Trials / Completed
CompletedNCT02415101
Timing of Resective Surgery After Neoadjuvant Chemoradiotherapy in Esophageal Cancer
Randomized Clinical Trial Comparing the Timing of Resective Surgery After Neoadjuvant Chemoradiotherapy in Cancer of the Esophagus or Gastric Cardia
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 202 (actual)
- Sponsor
- Karolinska University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This study compares outcomes with regard to the timing of resective surgery after neoadjuvant chemoradiotherapy (CRT) in cancer of the esophagus or gastric cardia. Patients are randomised to surgery either conventional 4-6 or 10-12 weeks after termination of CRT. The study hypothesis is that a longer delay improves histological response and decreases the risk of postoperative morbidity and mortality.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Resective surgery |
Timeline
- Start date
- 2015-02-01
- Primary completion
- 2019-04-19
- Completion
- 2024-08-05
- First posted
- 2015-04-14
- Last updated
- 2025-09-03
Locations
1 site across 1 country: Sweden
Source: ClinicalTrials.gov record NCT02415101. Inclusion in this directory is not an endorsement.